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NEW ANTIBIOTICS FOR MAC MAC

Several studies identified specific NTM patient factors that were associated with progressive disease and led to more immediate antibiotic treatment initiation. Read more about the factors and circumstances that should get you thinking about treatment:

The decision to initiate antibiotic treatment should be individualized based on a risk-benefit analysis, taking into account patient symptoms, radiologic findings, and microbiologic results. When should I consider treatment immediately?Īfter confirming an NTM lung disease diagnosis, the 2020 NTM Guidelines recommend treatment initiation rather than “watchful waiting” in certain diagnosed patients, especially in those with positive AFB sputum smears and cavitary disease.

NEW ANTIBIOTICS FOR MAC MAC

Retrospective studies have shown that most MAC patients who convert on treatment do so within 6 months after starting treatment 8-10.

The 2020 NTM Guidelines recommend frequent follow-up visits after initiating MAC treatment, including obtaining sputum cultures every 1 to 2 months to assess response 1.

When you decide to initiate antibiotic treatment, the 2020 NTM Guidelines recommend a multidrug regimen 1.

62.5% (305/488) of untreated MAC patients experienced progressive disease that required initiation of antibiotic treatment within 3 years of diagnosis 3.

Studies show that a majority of untreated MAC lung disease patients will have progressive disease resulting in the need for antibiotic treatment 3,7.

If you decide not to initiate antibiotic treatment, an active monitoring plan is recommended by the 2020 NTM Guidelines 1.

Certain factors like cavitary disease and low BMI have been associated with progressive disease and may necessitate earlier consideration of antibiotic treatment 1-6.

1Īfter confirming an NTM lung disease diagnosis:

When making treatment decisions for nontuberculous mycobacterial (NTM) lung disease, such as Mycobacterium avium complex (MAC) lung disease, the 2020 NTM Guidelines recommend initiating treatment rather than watchful waiting for certain diagnosed patients and suggest that the decision should be individualized based on a combination of clinical factors. The 2020 NTM Guidelines recommend treatment initiation rather than "watchful waiting" in certain diagnosed patients.